Sexually transmitted diseases (STDs) are on the rise — but so is access to testing. In a world where convenience and privacy matter more than ever, at-home STD testing is reshaping how Americans approach sexual health.
Discreet, fast, and accurate, these modern kits can be ordered online and completed in the privacy of your own home. No awkward clinic visits. No waiting rooms. Just reliable results — often in a matter of days.
But with dozens of providers promising everything from 24-hour turnaround to full-panel screenings, how do you know which service is right for you? Let’s break down why STD testing is more important than ever — and which companies are leading the pack in 2025.
Why STD Testing Matters More Than Ever
According to the CDC, one in five Americans has a sexually transmitted infection (STI), with nearly 26 million new infections each year. And many people have no idea — because most STDs show no symptoms.
Untreated infections can lead to serious health complications, including:
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Infertility (chlamydia, gonorrhea)
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Neurological damage (syphilis)
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Increased HIV risk
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Birth complications
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Chronic pain or pelvic inflammatory disease
Regular screening is crucial — especially if you’re sexually active, have multiple partners, or are starting a new relationship.
What At-Home STD Tests Can Detect
Most at-home test kits cover these common infections:
STD | Symptoms | Detectable With |
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Chlamydia | Often asymptomatic | Urine, vaginal swab |
Gonorrhea | Pain, discharge, burning | Urine, vaginal swab |
Syphilis | Sores, rashes, fever | Finger-prick blood test |
HIV | Flu-like symptoms or none | Finger-prick blood test |
Herpes (HSV-2) | Blisters or none | Blood test |
Trichomoniasis | Odor, itching, discharge | Urine or vaginal swab |
HPV | Usually asymptomatic | Often tested via Pap smear |
Hepatitis B/C | Fatigue, liver issues | Blood test |
Most test kits are designed to detect active infections through a mix of urine samples, genital swabs, or finger-prick blood tests.
Best At-Home STD Testing Companies in 2025
1. Everlywell
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Tests Offered: Chlamydia, gonorrhea, trichomoniasis, syphilis, hepatitis C, HIV, and more
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Results: 2–5 days via secure portal
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Physician Review: Included
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Follow-Up: Telehealth consult and prescription if positive
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Cost: $49–$149 (insurance not accepted)
Best For: General wellness users who want a straightforward, affordable test with fast results.
2. LetsGetChecked
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Tests Offered: Basic to Complete 8-panel STD test
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Results: 2–5 days; results via mobile app
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Physician Review: Yes, with free nurse support
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Follow-Up: Treatment available for select infections
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Cost: $89–$249; subscription plans available
Best For: Those who want routine testing, with options to test regularly at a discount.
3. Nurx
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Tests Offered: Full STD test kit (chlamydia, gonorrhea, HIV, syphilis, hepatitis C, and more)
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Results: 7 days average
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Physician Review: Yes — every test reviewed by a licensed provider
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Follow-Up: Free prescription and delivery of treatment when applicable
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Cost: $75–$150; insurance accepted
Best For: Those who want continuity of care, prescriptions, and insurance billing.
4. myLAB Box
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Tests Offered: Everything from individual tests to comprehensive 14-panel screening kits
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Results: 2–5 days
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Physician Review: Yes
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Follow-Up: Telehealth and prescription treatment included
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Cost: $79–$369; bundles and couples’ kits available
Best For: People wanting full-spectrum testing and flexible, customizable kits.
5. STDcheck.com
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Tests Offered: 10-panel tests, individual options, and same-day lab testing at 4,500+ locations
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Results: As fast as 24–48 hours
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Physician Review: Yes
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Follow-Up: Doctor consult and treatment coordination
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Cost: $99–$198 (FSA/HSA accepted)
Best For: Those who prefer anonymous lab testing with ultra-fast turnaround.
How It Works
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Order a kit online – Choose your test(s) and provide shipping info
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Collect your sample – Urine, swab, or finger-prick blood, depending on test
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Send it back – Prepaid shipping labels are included
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Get results online – Usually within 2 to 5 days
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Follow up – Telehealth consults and treatment available through most services
Privacy and Accuracy
All reputable at-home STD testing companies follow CLIA-certified lab standards (same as hospitals). Tests are typically 95–99% accurate when used correctly and reviewed by licensed professionals.
✅ Tests are shipped in discreet packaging
✅ Results are accessed through secure portals
✅ Many services offer free treatment and follow-up if you test positive
Who Should Test and How Often?
CDC guidelines suggest:
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Annual testing for all sexually active people under 25
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Every 3–6 months for people with multiple partners or in non-monogamous relationships
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Immediate testing after unprotected sex or symptoms
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Before starting a new relationship
Final Thoughts
STD testing is no longer something to dread — and in 2025, it’s never been easier. Whether you’re looking for peace of mind, staying proactive, or managing your sexual health discreetly, at-home STD kits offer private, fast, and reliable options.
Everlywell and LetsGetChecked offer fast, accessible testing. Nurx is best for full-service care and prescriptions. myLAB Box excels at customization, and STDcheck.com is great for lab-based speed.
One thing is clear: the stigma is fading, and the tools are better than ever. When in doubt, test. Your health — and your future partners — will thank you.